An Injectable Neural Stimulation Electrode Made from an In-Body Curing Polymer/Metal Composite.

ABSTRACT: Implanted neural stimulation and recording devices hold vast potential to treat a variety of neurological conditions, but the invasiveness, complexity, and cost of the implantation procedure greatly reduce access to an otherwise promising therapeutic approach. To address this need, a novel electrode that begins as an uncured, flowable prepolymer that can be injected around a neuroanatomical target to minimize surgical manipulation is developed. Referred to as the Injectrode, the electrode conforms to target structures forming an electrically conductive interface which is orders of magnitude less stiff than conventional neuromodulation electrodes. To validate the Injectrode, detailed electrochemical and microscopy characterization of its material properties is performed and the feasibility

SUBMITTER: Trevathan JK 

PROVIDER: S-EPMC10425988 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature