¹⁸F-DCFPyL PSMA-PET affects management of salvage radiotherapy for post-prostatectomy patients with biochemical failure: A matched cohort study.

ABSTRACT:

Introduction

Our objective was to assess the effect of ¹⁸F-DCFPyL prostate-specific membrane antigen (PSMA) positron emission tomography (PET) on the management and outcomes of patients receiving salvage radiotherapy following biochemical failure (BF) post-radical prostatectomy (RP) using a matched cohort analysis.

Methods

A PSMA-PET cohort of patients with BF post-RP was identified through a prospective registry. Patients from this registry were included if they did not have disease outside of the pelvis and underwent salvage radiotherapy to the prostate and/or pelvis. Case-control matching was performed with a contemporary cohort of patients with BF post-RP without PSMA-PET information.

Results

Forty-four patients were included in the PSMA-PET cohort and

SUBMITTER: Arifin AJ 

PROVIDER: S-EPMC10426430 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature