Randomized Controlled Trials in ICU in the Four Highest-Impact General Medicine Journals.

ABSTRACT:

Objective

To study ICU trials published in the four highest-impact general medicine journals by comparing them with concurrently published non-ICU trials in the same journals.

Data sources

PubMed was searched for randomized controlled trials (RCTs) published between January 2014 and October 2021 in the New England Journal of Medicine , The Lancet , the Journal of the American Medical Association , and the British Medical Journal.

Study selection

Original RCT publications investigating any type of intervention in any patient population.

Data extraction

ICU RCTs were defined as RCTs exclusively including patients admitted to the ICU. Year and journal of publication, sample size, study design, funding source, study outcome, type of intervention, Fragility Index (F

SUBMITTER: Kampman JM 

PROVIDER: S-EPMC10426774 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature