A decentralized, prospective, observational study to collect real-world data from patients with myasthenia gravis using smartphones.

ABSTRACT:

Introduction

We conducted a 3-month, prospective study in a population of patients with Myasthenia Gravis (MG), utilizing a fully decentralized approach for recruitment and monitoring (ClinicalTrials.gov Identifier: NCT04590716). The study objectives were to assess the feasibility of collecting real-world data through a smartphone-based research platform, in order to characterize symptom involvement during MG exacerbations.

Methods

Primary data collection included daily electronically recorded patient-reported outcomes (ePROs) on the presence of MG symptoms, the level of symptom severity (using the MG-Activities of Daily Living assessment, MG-ADL), and exacerbation status. Participants were also given the option to contribute data on their physical activity levels from their

SUBMITTER: Steyaert S 

PROVIDER: S-EPMC10427188 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature