Drug-Coated Balloon-Only Strategy for De Novo Coronary Artery Disease: A Meta-analysis of Randomized Clinical Trials.

ABSTRACT:

Backgrounds

Many clinical trials have demonstrated the value of drug-coated balloons (DCB) for in-stent restenosis. However, their role in de novo lesions is not well documented. The aim of this study is to evaluate the safety and efficacy of the DCB-only strategy compared to other percutaneous coronary intervention strategies for de novo coronary lesions.

Methods

The PubMed, Embase, Web of Science, and Cochrane Library Central Register of Controlled Trials (CENTRAL) electronic databases were searched for randomized controlled trials published up to May 6, 2023. The primary outcomes were major adverse cardiac events and late lumen loss.

Results

A total of eighteen trials with 3336 participants were included. Compared with drug-eluting stents, the DCB-only strategy was

SUBMITTER: Zhang W 

PROVIDER: S-EPMC10427238 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature