Use of overactive bladder anticholinergic medications associated with falls leading to emergency department visits: results from the ADRED study.

ABSTRACT:

Purpose

Drug intake might be a modifiable factor for the individual fall-risk of older adults, and anticholinergic properties of drugs need to be considered. This study is aimed at analyzing the association of older adults' individual anticholinergic load with particular focus on use of overactive bladder anticholinergic medications with falls in multi-medicated patients.

Materials and methods

Cases of the prospective, observational, multi-center study on adverse drug reactions leading to emergency departments (ADRED study) between 2015 and 2018 in Germany were analyzed comparing the exposure of overactive bladder anticholinergic medications on the chance to present with a fall with patients without exposure. Logistic regression analysis was used adjusting for pre-existing c

SUBMITTER: Just KS 

PROVIDER: S-EPMC10427532 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature