Real-World Evaluation of the Management, Treatment Pathways and Outcome of Melanoma Patients with Target Therapies in Italy.

ABSTRACT:

Introduction

In recent years, an increasing trend in the incidence of melanoma has been observed in Europe. Although early diagnosis and prompt intervention with local resection often results in positive outcomes, conversely, metastatic disease is still clinically challenging with a poor prognosis and a 5-year survival of around 30%. The growing awareness of melanoma biology and of antitumor immune responses has allowed the development of novel therapies targeted at specific molecular alterations occurring at advanced stages. This real-world analysis examined patients with melanoma in Italy, focusing on treatment patterns, outcome, time to discontinuation (TTD), and resource consumption.

Methods

Two retrospective observational analyses were conducted for BRAF+ patients with

SUBMITTER: Marcon IG 

PROVIDER: S-EPMC10427535 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature