Seroprevalence of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) antibodies among healthcare personnel in the Midwestern United States, September 2020-April 2021.

ABSTRACT:

Objective

To determine the prevalence of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) IgG nucleocapsid (N) antibodies among healthcare personnel (HCP) with no prior history of COVID-19 and to identify factors associated with seropositivity.

Design

Prospective cohort study.

Setting

An academic, tertiary-care hospital in St. Louis, Missouri.

Participants

The study included 400 HCP aged ≥18 years who potentially worked with coronavirus disease 2019 (COVID-19) patients and had no known history of COVID-19; 309 of these HCP also completed a follow-up visit 70-160 days after enrollment. Enrollment visits took place between September and December 2020. Follow-up visits took place between December 2020 and April 2021.

Methods

At each study visit, pa

SUBMITTER: Bosserman RE 

PROVIDER: S-EPMC10428156 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature