Diuretic response to Ringer's solution is normal shortly after awakening from general anaesthesia: a retrospective kinetic analysis.

ABSTRACT:

Background

The elimination of Ringer's solution is severely depressed during general anaesthesia, but the degree to which this continues postoperatively is poorly established.

Methods

An intravenous infusion of Ringer's acetate solution 20 ml kg^-1 was administered over 60 min in 12 patients undergoing laparoscopic cholecystectomy. Population kinetic analysis was performed based on repeated measurements of blood haemoglobin concentration and urinary excretion over 240 min regardless of when the operations were finished. The analysis contrasted the periods before and after awakening from general anaesthesia and compared them with data from 18 volunteers who received the same fluid at the same rate.

Results

Patients were monitored for approximately 2 h after a

SUBMITTER: Hahn RG 

PROVIDER: S-EPMC10430821 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature