The impact and role of identified long noncoding RNAs in nonalcoholic fatty liver disease: A narrative review.

ABSTRACT:

Background

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, but its mechanism and pathophysiology remain unclear. Long noncoding RNAs (lncRNAs) may exert a vital influence on regulating various biological functions in NAFLD.

Methods

The databases such as Google Scholar, PubMed, and Medline were searched using the following keywords: nonalcoholic fatty liver disease, nonalcoholic fatty liver disease, NAFLD, nonalcoholic steatohepatitis, nonalcoholic steatohepatitis, NASH, long noncoding RNAs, and lncRNAs. Considering the titles and abstracts, unrelated studies were excluded. The authors evaluated the full texts of the remaining studies.

Results

We summarized the current knowledge of lncRNAs and the main signaling pathways of lncRNAs

SUBMITTER: Shi N 

PROVIDER: S-EPMC10431402 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature