Logistic-Nomogram model based on red blood cell parameters to differentiate thalassemia trait and iron deficiency anemia in southern region of Fujian Province, China.

ABSTRACT:

Background

Differentiation between thalassemia trait (TT) and iron deficiency anemia (IDA) is challenging and costly. This study aimed to construct and evaluate a model based on red blood cell (RBC) parameters to differentiate TT and IDA in the southern region of Fujian Province, China.

Methods

RBC parameters of 364 TT patients and 316 IDA patients were reviewed. RBC parameter-based Logistic-Nomogram model to differentiate between TT and IDA was constructed by multivariate logistic regression analysis plus nomogram, and then compared with 22 previously reported differential indices.

Results

The patients were randomly selected to a training cohort (n_TT  = 248, n_IDA  = 223) and a validation cohort (n_TT  = 116, n_IDA  = 93). In

SUBMITTER: Xu M 

PROVIDER: S-EPMC10431415 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature