Vaccine effectiveness in symptom and viral load mitigation in COVID-19 breakthrough infections in South Korea.

ABSTRACT:

Objectives

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine effectiveness in coronavirus disease (COVID-19) patients with breakthrough infections has not been established in South Korea. To address this, we assessed the impact of vaccination on symptom occurrence and viral load.

Methods

We performed a retrospective cohort study of 9,030 COVID-19 patients enrolled between February and November 2021. The impact of vaccination on the incidence of symptoms and viral load as indicated by cycle threshold (Ct) values of RdRp and E genes was evaluated using relative risks (RRs) and 95% confidence intervals (95% CIs).

Results

Compared with unvaccinated patients, fully vaccinated patients were associated with a reduced symptom onset of cough, sputum, and mya

SUBMITTER: Jang J 

PROVIDER: S-EPMC10431655 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature