Ontology highlight
ABSTRACT: Objective
To compare the impact of a teen club model to the standard care model on HIV treatment outcomes among adolescents (10-19 years of age).Design
Retrospective cohort study.Setting
HIV clinics in Neno district, Malawi.Participants
Adolescents living with HIV enrolled in teen clubs (n=235) and matched participants in standard HIV care (n=297).Outcome measures
Attrition from HIV care, defined as a combination of treatment outcomes 'died', 'defaulted' and 'transferred out'.Results
Over a 4-year follow-up period, adolescents who participated in the teen club had a significantly higher likelihood of remaining in care than those who did not (HR=2.80; 95% CI: 1.46 to 5.34). Teen clubs also increased the probability of having a recent measured viral load (VL) and BMI, but did not change the probability of VL suppression. The age at antiretroviral treatment initiation below 15 years (aHR=0.37; 95% CI: 0.17 to 0.82) reduced the risk of attrition from HIV care, while underweight status (aHR=3.18; 95% CI: 1.71 to 5.92) increased the risk of attrition, after controlling for sex, WHO HIV staging and teen club participation.Conclusions
The teen club model has the potential to improve treatment outcomes among adolescents in rural Neno district. However, in addition to retaining adolescents in HIV care, greater attention is needed to treatment adherence and viral suppression in this special population. Further understanding of the contextual factors and barriers that adolescents in rural areas face could further improve the teen club model to ensure high-quality HIV care and quality of life.
SUBMITTER: Trapence CP
PROVIDER: S-EPMC10432624 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Trapence Clement Patrick CP Kanyenda Chisomo C Muyila Fainala F Ndarama Enoch Pl EP Suffrin Dimitri D Connolly Emilia E Kachimanga Chiyembekezo C Kulinkina Alexandra V AV
BMJ open 20230816 8
<h4>Objective</h4>To compare the impact of a teen club model to the standard care model on HIV treatment outcomes among adolescents (10-19 years of age).<h4>Design</h4>Retrospective cohort study.<h4>Setting</h4>HIV clinics in Neno district, Malawi.<h4>Participants</h4>Adolescents living with HIV enrolled in teen clubs (n=235) and matched participants in standard HIV care (n=297).<h4>Outcome measures</h4>Attrition from HIV care, defined as a combination of treatment outcomes 'died', 'defaulted' a ...[more]