Participant Perceptions in a Long-term Clinical Trial of Autosomal Dominant Polycystic Kidney Disease.

ABSTRACT:

Rationale & objective

The development of new therapies for autosomal dominant polycystic kidney disease requires clinical trials to be conducted efficiently. In this study, the factors affecting the recruitment and retention of participants enrolled in a 3-year randomized controlled trial in autosomal dominant polycystic kidney disease were investigated.

Study design

Qualitative study.

Setting & participants

All participants (N=187) were invited to complete a 16-item questionnaire at the final study visit of the primary trial. Participants were recruited to complete a semistructured interview using purposeful sampling according to age, self-reported gender, and randomization group.

Analytical approach

Descriptive statistics were used for demographic data and qu

SUBMITTER: Amin S 

PROVIDER: S-EPMC10432794 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature