Wastewater-based epidemiology: the crucial role of viral shedding dynamics in small communities.

ABSTRACT:

Background

Wastewater surveillance (WWS) of pathogens is a rapidly evolving field owing to the 2019 coronavirus disease pandemic, which brought about a paradigm shift in public health authorities for the management of pathogen outbreaks. However, the interpretation of WWS in terms of clinical cases remains a challenge, particularly in small communities where large variations in pathogen concentrations are routinely observed without a clear relation to clinical incident cases.

Methods

Results are presented for WWS from six municipalities in the eastern part of Canada during the spring of 2021. We developed a numerical model based on viral kinetics reduction functions to consider both prevalent and incident cases to interpret the WWS data in light of the reported clinical case

SUBMITTER: Rioux MD 

PROVIDER: S-EPMC10433918 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature