Optimisation of GraPhage13 macro-dispersibility via understanding the pH-dependent ionisation during self-assembly: towards the manufacture of graphene-based nanodevices.

ABSTRACT: GraPhage13 aerogels (GPAs) are micro-porous structures generated through the self-assembly of graphene oxide (GO) and M13 bacteriophage. As GPA fabrication involves the aggregation of GO and M13 in aqueous solution, we aim to understand its dispersibility across a wide pH range. Herein, a novel technique has been developed to relate the ionisation of functional groups to the surface charge, offering insights into the conditions required for GPA fabrication and the mechanism behind its self-assembly. The aggregation of GO and M13 was observed between pH 2-6 and exhibited dependence on the surface charge of the resulting aggregate with the M13 bacteriophage identified as the primary factor contributing to this, whilst originating from the ionisation of its functional groups. In contrast, GO

SUBMITTER: Stokes K 

PROVIDER: S-EPMC10433945 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature