Estragole Inhibits Growth and Aflatoxin Biosynthesis of <i>Aspergillus flavus</i> by Affecting Reactive Oxygen Species Homeostasis.

ABSTRACT: A variety of essential oils and edible compounds have been widely recognized for their antifungal activity in recent years. In this study, we explored the antifungal activity of estragole from Pimenta racemosa against Aspergillus flavus and investigated the underlying mechanism of action. The results showed that estragole had significant antifungal activity against A. flavus, with a minimum inhibitory concentration of 0.5 μL/mL against spore germination. Additionally, estragole inhibited the biosynthesis of aflatoxin in a dose-dependent manner, and aflatoxin biosynthesis was significantly inhibited at 0.125 μL/mL. Pathogenicity assays showed that estragole had potential antifungal activity against A. flavus in peanut and corn grains by inhibiting conidia and aflatoxin production. Transcrip

SUBMITTER: Liang L 

PROVIDER: S-EPMC10434025 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature