Absence of Staphylococcus aureus in Wild Populations of Fish Supports a Spillover Hypothesis.

ABSTRACT: Staphylococcus aureus is a human commensal and opportunistic pathogen that also infects other animals. In humans and livestock, where S. aureus is most studied, strains are specialized for different host species. Recent studies have also found S. aureus in diverse wild animals. However, it remains unclear whether these isolates are also specialized for their hosts or whether their presence is due to repeated spillovers from source populations. This study focuses on S. aureus in fish, testing the spillover hypothesis in two ways. First, we examined 12 S. aureus isolates obtained from the internal and external organs of a farmed fish. While all isolates were from clonal complex 45, genomic diversity indicates repeated acquisition. The presence of a φSa3 prophage containing human immune evasi

SUBMITTER: Matuszewska M 

PROVIDER: S-EPMC10434045 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature