The Vaginal Microbiota of Pregnant Women Varies with Gestational Age, Maternal Age, and Parity.

ABSTRACT: The composition of the vaginal microbiota is heavily influenced by pregnancy and may factor into pregnancy complications, including spontaneous preterm birth. However, results among studies have been inconsistent due, in part, to variation in sample sizes and ethnicity. Thus, an association between the vaginal microbiota and preterm labor continues to be debated. Yet, before assessing associations between the composition of the vaginal microbiota and preterm labor, a robust and in-depth characterization of the vaginal microbiota throughout pregnancy in the specific study population under investigation is required. Here, we report a large longitudinal study (n = 474 women, 1,862 vaginal samples) of a predominantly African-American cohort-a population that experiences a relatively hig

SUBMITTER: Romero R 

PROVIDER: S-EPMC10434204 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature