Enhancement of cell migration and wound healing by nano-herb ointment formulated with biosurfactant, silver nanoparticles and Tridax procumbens

ABSTRACT:

Introduction

Ointments are generally used as a therapeutic agent for topical medication or transdermal drug delivery, such as wound healing and skin lesions.

Methods

In this study, Tridax procumbens plant extract (0.7 g/mL) was used to prepare herbal-infused oil as the oil phase and gelatin-stabilized silver nanoparticle (G-AgNPs) (0.3 g/mL) as the aqueous phase. To blend the oil and aqueous phases, rhamnolipid biosurfactant with a critical micelle concentration of 55 mg/L from strain Pseudomonas aeruginosa PP4 has been used for herb ointment preparation. The average size of the synthesized G-AgNPs was observed between 10–30 nm and confirmed as spherical-shaped particles by TEM analysis. Subsequently, GC–MS and FTIR characterization are used to confirm herb ointment’s che

SUBMITTER: Muthukumar B 

PROVIDER: S-EPMC10434256 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature