Intermittent energy restriction changes the regional homogeneity of the obese human brain

ABSTRACT:

Background

Intermittent energy restriction (IER) is an effective weight loss strategy. However, the accompanying changes in spontaneous neural activity are unclear, and the relationship among anthropometric measurements, biochemical indicators, and adipokines remains ambiguous.

Methods

Thirty-five obese adults were recruited and received a 2-month IER intervention. Data were collected from anthropometric measurements, blood samples, and resting-state functional magnetic resonance imaging at four time points. The regional homogeneity (ReHo) method was used to explore the effects of the IER intervention. The relationships between the ReHo values of altered brain regions and changes in anthropometric measurements, biochemical indicators, and adipokines (leptin and adiponecti

SUBMITTER: Li Z 

PROVIDER: S-EPMC10434787 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature