Chemotherapy induced right ventricular cardiomyopathy; a systematic review and meta-analysis

ABSTRACT:

Background

Left ventricular dysfunction and cardiomyopathy are well documented adverse effects associated with chemotherapy agents. Limited information exists regarding the impact of chemotherapeutic agents on the integrity and function of the right ventricle (RV).

Objectives

The current metanalysis compared pre- chemotherapy versus post- chemotherapy RV parameters measured on 2D echocardiography in patients receiving anthracycline and/or trastuzumab across all breast cancer patients.

Methods

A systematic search across PubMed, EMBASE and Cochrane databases were performed from inception of the databases until November 2021 for relevant studies. We used the inverse variance method with a random effect model and DerSimonian and Laird method of Tau2 generation to cal

SUBMITTER: Theetha Kariyanna P 

PROVIDER: S-EPMC10434797 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature