The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster.

ABSTRACT: The genetic causes of phenotypic variation often differ depending on the population examined, particularly if the populations were founded by relatively small numbers of genotypes. Similarly, the genetic causes of phenotypic variation among similar traits (resistance to different xenobiotic compounds or pathogens) may also be completely different or only partially overlapping. Differences in genetic causes for variation in the same trait among populations suggests context dependence for how selection acts on those traits. Similarities in the genetic causes of variation for different traits, on the other hand, suggests pleiotropy which would also influence how natural selection shapes variation in a trait. We characterized immune defense against a natural Drosophila pathogen, the Gram-posit

SUBMITTER: Smith BR 

PROVIDER: S-EPMC10434897 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature