A brain-wide analysis maps structural evolution to distinct anatomical module.

ABSTRACT: The vertebrate brain is highly conserved topologically, but less is known about neuroanatomical variation between individual brain regions. Neuroanatomical variation at the regional level is hypothesized to provide functional expansion, building upon ancestral anatomy needed for basic functions. Classically, animal models used to study evolution have lacked tools for detailed anatomical analysis that are widely used in zebrafish and mice, presenting a barrier to studying brain evolution at fine scales. In this study, we sought to investigate the evolution of brain anatomy using a single species of fish consisting of divergent surface and cave morphs, that permits functional genetic testing of regional volume and shape across the entire brain. We generated a high-resolution brain atlas for

SUBMITTER: Kozol RA 

PROVIDER: S-EPMC10435234 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature