Magnetic resonance imaging and neuropsychological findings for predicting of cognitive deterioration in memory clinic patients.

ABSTRACT:

Objective

The severity of cerebral small vessel disease (SVD) on magnetic resonance imaging (MRI) has been assessed using hypertensive arteriopathy SVD and cerebral amyloid angiopathy (CAA)-SVD scores. In addition, we reported the modified CAA-SVD score including cortical microinfarcts and posterior dominant white matter hyperintensity. Each SVD score has been associated with cognitive function, but the longitudinal changes remain unclear. Therefore, this study prospectively examined the prognostic value of each SVD score, imaging findings of cerebral SVD, and neuropsychological assessment.

Methods

This study included 29 patients diagnosed with mild cognitive impairment or mild dementia at memory clinic in our hospital, who underwent clinical dementia rating (CDR) and brain

SUBMITTER: Matsuda K 

PROVIDER: S-EPMC10435295 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature