Tetramethylalloxazines as efficient singlet oxygen photosensitizers and potential redox-sensitive agents.

ABSTRACT: Tetramethylalloxazines (TMeAll) have been found to have a high quantum yield of singlet oxygen generation when used as photosensitizers. Their electronic structure and transition energies (S₀ → S_i, S₀ → T_i, T₁ → T_i) were calculated using DFT and TD-DFT methods and compared to experimental absorption spectra. Generally, TMeAll display an energy diagram similar to other derivatives belonging to the alloxazine class of compounds, namely π,π* transitions are accompanied by closely located n,π* transitions. Photophysical data such as quantum yields of fluorescence, fluorescence lifetimes, and nonradiative rate constants were also studied in methanol (MeOH), acetonitrile (ACN), and 1,2-dichloroethane (DCE). The transient absorptio

SUBMITTER: Golczak A 

PROVIDER: S-EPMC10435492 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature