Population-level benefits of increasing influenza vaccination uptake among Italian older adults: results from a granular panel model.

ABSTRACT:

Background

The impact of seasonal influenza vaccination (SIV) on mortality is still controversial; some studies have claimed that increasing vaccination coverage rates is beneficial, while others have found no significant association. This study aimed to construct a granular longitudinal dataset of local VCRs and assess their effect on pneumonia- and influenza-related (P&I) mortality among Italian adults aged ≥ 65 years.

Methods

NUTS-3 (nomenclature of territorial units for statistics) level data on SIV coverage were collected via a survey of local data holders. Fixed- and random-effects panel regression modeling, when adjusted for potential confounders, was performed to assess the association between local SIV coverage rates and P&I mortality in older adults.

Results

SUBMITTER: Domnich A 

PROVIDER: S-EPMC10435743 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature