Current imaging methods for assessing Graves` orbitopathy activity with particular emphasis on FDG-PET

ABSTRACT: The most frequent extrathyroidal Graves’ disease manifestation is Graves’ orbitopathy (GO). The treatment of GO is determined by its severity and activity. There is currently no reliable, impartial method for assessing it clinically or distinguishing fibrosis from active inflammatory disorders. Today, imaging methods including orbital ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) are frequently employed to show pathological abnormalities in the ocular adnexa of GO patients. In addition, a not widely accepted technique – 99mTc-DTPA SPECT – has some potential to evaluate retrobulbar inflammation in GO patients. However, FDG-PET/CT is possibly superior to other imaging modalities in detecting inflammation in GO and it may be useful in assessing disease activi

SUBMITTER: Ochmann A 

PROVIDER: S-EPMC10435873 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature