Structural evidence for elastic tethers connecting separating chromosomes in crane-fly spermatocytes.

ABSTRACT: Different types of anaphase bridges are reported to form between segregating chromosomes during cell division. Previous studies using laser microsurgery suggested that elastic tethers connect the telomeres of separating anaphase chromosomes in many animal meiotic and mitotic cells. However, structural evidence is lacking for their existence. In this study, by correlating live imaging with electron tomography, we examined whether visible structures connect separating telomeres in meiosis I of crane-fly primary spermatocytes. We found structures extending between separating telomeres in all stages of anaphase. The structures consist of two components: one is darkly stained, looking somewhat like chromatin, whereas the other is more lightly stained, appearing filamentous. Although in early an

SUBMITTER: Forer A 

PROVIDER: S-EPMC10435969 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature