Three-Dimensional Structural Phenotype of the Optic Nerve Head as a Function of Glaucoma Severity.

ABSTRACT:

Importance

The 3-dimensional (3-D) structural phenotype of glaucoma as a function of severity was thoroughly described and analyzed, enhancing understanding of its intricate pathology beyond current clinical knowledge.

Objective

To describe the 3-D structural differences in both connective and neural tissues of the optic nerve head (ONH) between different glaucoma stages using traditional and artificial intelligence-driven approaches.

Design, setting, and participants

This cross-sectional, clinic-based study recruited 541 Chinese individuals receiving standard clinical care at Singapore National Eye Centre, Singapore, and 112 White participants of a prospective observational study at Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania. The study was cond

SUBMITTER: Braeu FA 

PROVIDER: S-EPMC10436184 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature