Solvent-Induced Pathway Complexity of Supramolecular Polymerization Unveiled Using the Hansen Solubility Parameters.

ABSTRACT: Supramolecular building blocks assembling into helical aggregates are ubiquitous in the current literature, yet the role of solvents in these supramolecular polymerizations often remains elusive. Here, we present a systematic study that quantifies solvent-supramolecular polymer compatibility using the Hansen solubility parameters (δ_D, δ_H, and δ_P). We first studied the solubility space of the supramolecular building block triazine-1,3,5-tribenzenecarboxamide S-T. Due to its amphiphilic nature, a dual-sphere model based on 58 solvents was applied describing the solubility space of the monomeric state (green sphere) and supramolecular polymer state (blue sphere). To our surprise, further in-depth spectroscopic and morphological studies unveiled a

SUBMITTER: van der Tol JJB 

PROVIDER: S-EPMC10436269 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature