Establishment of a Mycoplasma hyorhinis challenge model in 5-week-old piglets.

ABSTRACT:

Introduction

Mycoplasma hyorhinis is an emerging swine pathogen with high prevalence worldwide. The main lesions caused are arthritis and polyserositis, and the clinical manifestation of the disease may result in significant economic losses due to decreased weight gain and enhanced medical costs. We aimed to compare two challenge routes to induce M. hyorhinis infection using the same clinical isolate.

Methods

Five-week-old, Choice hybrid pigs were inoculated on 2 consecutive days by intravenous route (Group IV-IV) or by intravenous and intraperitoneal routes (Group IV-IP). Mock-infected animals were used as control (control group). After the challenge, the clinical signs were recorded for 28 days, after which the animals were euthanized. Gross pathological and

SUBMITTER: Foldi D 

PROVIDER: S-EPMC10436309 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature