Rare phylotypes in stone, stool, and urine microbiomes are associated with urinary stone disease.

ABSTRACT: Introduction: In complex microbial communities, the importance of microbial species at very low abundance levels and their prevalence for overall community structure and function is increasingly being recognized. Clinical microbiome studies on urinary stone disease (USD) have indicated that both the gut and urinary tract microbiota are associated with the onset of the disease and that kidney stones them-selves harbor a complex, yet consistent and viable, microbiome. However, how rare phylotypes contribute to this association remains unclear. Delineating the contribution of rare and common phylotypes to urinary stone disease is important for the development of bacteriotherapies to promote urologic health. Methods: The objectives of the current report were to conduct a metaanal

SUBMITTER: Suryavanshi M 

PROVIDER: S-EPMC10436313 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature