Molecular regulatory mechanism of key LncRNAs in subclinical mastitic cows with folic acid supplementation.

ABSTRACT:

Background

Folic acid is a water-soluble B vitamin (B9), which is closely related to the body's immune and other metabolic pathways. The folic acid synthesized by rumen microbes has been unable to meet the needs of high-yielding dairy cows. The incidence rate of subclinical mastitis in dairy herds worldwide ranged between 25%~65% with no obvious symptoms, but it significantly causes a decrease in lactation and milk quality. Therefore, this study aims at exploring the effects of folic acid supplementation on the expression profile of lncRNAs, exploring the molecular mechanism by which lncRNAs regulate immunity in subclinical mastitic dairy cows.

Results

The analysis identified a total of 4384 lncRNA transcripts. Subsequently, differentially expressed lncRNAs in the comparison

SUBMITTER: Liu X 

PROVIDER: S-EPMC10436419 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature