Fertility loss: negative effects of environmental toxicants on oogenesis.

ABSTRACT: There has been a global decline in fertility rates, with ovulatory disorders emerging as the leading cause, contributing to a global lifetime infertility prevalence of 17.5%. Formation of the primordial follicle pool during early and further development of oocytes after puberty is crucial in determining female fertility and reproductive quality. However, the increasing exposure to environmental toxins (through occupational exposure and ubiquitous chemicals) in daily life is a growing concern; these toxins have been identified as significant risk factors for oogenesis in women. In light of this concern, this review aims to enhance our understanding of female reproductive system diseases and their implications. Specifically, we summarized and categorized the environmental toxins that can aff

SUBMITTER: Yao X 

PROVIDER: S-EPMC10436557 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature