Outcomes among patients undergoing transcatheter aortic valve replacement with very low baseline gradients

ABSTRACT:

Background

While there is evidence that patients with low-flow, low-gradient aortic stenosis (AS) benefit from transcatheter aortic valve replacement (TAVR), data are lacking regarding outcomes of patients with a very low gradient (VLG).

Methods

In this retrospective, single-center study of patients with severe AS who underwent TAVR, three groups were defined using baseline mean aortic valve gradient: VLG (≤25 mmHg), low gradient (LG, 26–39 mmHg), and high gradient (HG, ≥40 mmHg). The primary outcome was the composite of Kansas City Cardiomyopathy Questionnaire (KCCQ)-12 of <45, decrease in KCCQ-12 of ≥10 compared with baseline, or death at 1 year.

Results

One-thousand six patients were included: 571 HG, 353 LG, and 82 VLG. The median age was 82.1 years [interqua

SUBMITTER: Rahman F 

PROVIDER: S-EPMC10436597 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature