Statistical modeling of gut microbiota for personalized health status monitoring.

ABSTRACT:

Background

The gut microbiome is closely associated with health status, and any microbiota dysbiosis could considerably impact the host's health. In addition, many active consortium projects have generated many reference datasets available for large-scale retrospective research. However, a comprehensive monitoring framework that analyzes health status and quantitatively present bacteria-to-health contribution has not been thoroughly investigated.

Methods

We systematically developed a statistical monitoring diagram for personalized health status prediction and analysis. Our framework comprises three elements: (1) a statistical monitoring model was established, the health index was constructed, and the health boundary was defined; (2) healthy patterns were identified among hea

SUBMITTER: Zhu J 

PROVIDER: S-EPMC10436630 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature