Association between cumulative atherogenic index of plasma exposure and risk of myocardial infarction in the general population.

ABSTRACT:

Background

Atherogenic index of plasma (AIP) has been confirmed as a novel marker for myocardial infarction (MI), but few evidence on the long-term AIP and MI risk in general populations. We thus aimed to evaluate the relationships of cumulative exposure to AIP and its accumulation time course with the risk of MI.

Methods

A total of 54,440 participants were enrolled in the Kailuan study. Time-weighted cumulative AIP was calculated as the weighted sum of the mean AIP value for each time interval, then normalized by total exposure duration, the exposure duration was from 2006 to 2010. Duration of high AIP exposure was defined as the duration with high AIP and ranged from 0 to 6 years. The time course of AIP accumulation was categorized by the combination of time-weighted cumul

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC10436658 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature