Detection of COPD in the SUMMIT Study lung cancer screening cohort using symptoms and spirometry.

ABSTRACT:

Background

COPD is a major comorbidity in lung cancer screening (LCS) cohorts, with a high prevalence of undiagnosed COPD. Combining symptom assessment with spirometry in this setting may enable earlier diagnosis of clinically significant COPD and facilitate increased understanding of lung cancer risk in COPD. In this study, we wished to understand the prevalence, severity, clinical phenotype and lung cancer risk of individuals with symptomatic undiagnosed COPD in a LCS cohort.

Methods

16 010 current or former smokers aged 55-77 years attended a lung health check as part of the SUMMIT Study. A respiratory consultation and spirometry were performed alongside LCS eligibility assessment. Those with symptoms, no previous COPD diagnosis and airflow obstruction were labelled as un

SUBMITTER: Tisi S 

PROVIDER: S-EPMC10436757 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature