Simulation of Cortical and Cancellous Bone to Accelerate Tissue Regeneration.

ABSTRACT: Different tissues have complex anisotropic structures to support biological functions. Mimicking these complex structures in vitro remains a challenge in biomaterials designs in support of tissue regeneration. Here, inspired by different types of silk nanofibers, a composite materials strategy was pursued towards this challenge. A combination of fabrication methods was utilized to achieve separate control of amorphous and beta-sheet rich silk nanofibers in the same solution. Aqueous solutions containing these two structural types of silk nanofibers were then simultaneously treated with an electric field and with ethylene glycol diglycidyl ether (EGDE). Under these conditions, the beta-sheet rich silk nanofibers in the mixture responded to the electric field while the amorphous nanof

SUBMITTER: Fan Z 

PROVIDER: S-EPMC10437128 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature