Effectiveness of successive booster vaccine doses against SARS-CoV-2 related mortality in residents of long-term care facilities in the VIVALDI study.

ABSTRACT:

Background

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused severe disease in unvaccinated long-term care facility (LTCF) residents. Initial booster vaccination following primary vaccination is known to provide strong short-term protection, but data are limited on duration of protection and the protective effect of further booster vaccinations.

Objective

To evaluate the effectiveness of third, fourth and fifth dose booster vaccination against SARS-CoV-2 related mortality amongst older residents of LTCFs.

Design

Prospective cohort study.

Setting

LTCFs for older people in England participating in the VIVALDI study.

Methods

Residents aged >65 years at participating LTCFs were eligible for inclusion if they had at least one polymerase chai

SUBMITTER: Stirrup O 

PROVIDER: S-EPMC10438206 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature