Approach to the Patient: The Evaluation and Management of Men ≥50 Years With Low Serum Testosterone Concentration.
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ABSTRACT:
SUBMITTER: Grossmann M
PROVIDER: S-EPMC10438885 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
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Approach to the Patient: The Evaluation and Management of Men ≥50 Years With Low Serum Testosterone Concentration.
Grossmann Mathis M Jayasena Channa N CN Anawalt Bradley D BD
The Journal of clinical endocrinology and metabolism 20230801 9
Although testosterone replacement in men with classic hypogonadism due to an identified pathology of the hypothalamic-pituitary-testicular axis is uncontroversial, the role of testosterone treatment for men with age-related declines in circulating testosterone is unclear. This is due to the lack of large, long-term testosterone therapy trials assessing definitive clinical endpoints. However, men ≥50 years of age, particularly those who have a body mass index >25 kg/m2 and multiple comorbidities, ...[more]
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