Trends in HOMA-IR values among South Korean adolescents from 2007-2010 to 2019-2020: a sex-, age-, and weight status-specific analysis.

ABSTRACT:

Background/objectives

An increase in obesity prevalence may lead to an increase in the HOMA-IR value. This study aimed to investigate changes in age- and sex-specific homeostasis model assessment of insulin resistance (HOMA-IR) values among South Korean adolescents, using data from the Korean National Health and Nutrition Examination Survey (KNHANES) IV, V, and VIII conducted between 2007-2010 and 2019-2020.

Subjects/methods

Overall, 4621 adolescents aged 10-18 years were evaluated, including 3473 from the 2007-2010 dataset and 1148 from the 2019-2020 dataset. The mean HOMA-IR values and percentile curves were evaluated by age, sex, and weight status.

Results

The mean HOMA-IR values peaked at puberty in both sexes and further increased during puberty in the 2019-2020

SUBMITTER: Kim S 

PROVIDER: S-EPMC10439007 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature