Troponin dependent 30-day mortality in patients with acute pulmonary embolism.

ABSTRACT:

Background

Troponin concentrations above upper reference are associated with increased mortality in patients with pulmonary embolism (PE). We aimed to assess whether risk of 30-day mortality increases in a dose-response relationship with concentration of troponin.

Methods

Using Danish national registries, we identified patients ≥ 18 years of age hospitalized with first-time PE between 2013 and 2018 and available troponin measurements - 1/+1 day from admission. Patients were stratified into quintiles by increasing troponin concentration. Risk of 30-day mortality was assessed performing cumulative mortality curves and Cox regression model comparing the troponin quintiles.

Results

We identified 5,639 PE patients of which 3,278 (58%) had a troponin concentration above upp

SUBMITTER: Sonne-Holm E 

PROVIDER: S-EPMC10439039 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature