Crystal-structure determination and Hirshfeld surface analysis of two new thio-phene derivatives: (E)-N-{2-[2-(benzo[b]thio-phen-2-yl)ethen-yl]-5-fluoro-phen-yl}benzene-sulfonamide and (E)-N-{2-[2-(benzo[b]thio-phen-2-yl)ethen-yl]-5-fluoro-phen-yl}-N-(but-2-yn-1-yl)benzene-sulfonamide.

ABSTRACT: In the title compounds, C₂₂H₁₆FNO₂S₂ (I) and C₂₆H₂₀FNO₂S₂ (II), the benzo-thio-phene rings are essentially planar with maximum deviations of 0.009 (1) and 0.001 (1) Å for the carbon and sulfur atom in compounds I and II, respectively. In I, the thio-phene ring system is almost orthogonal to the phenyl ring attached to the sulfonyl group, with a dihedral angle of 77.7 (1)°. In compound I, the mol-ecular structure is stabilized by weak C-H⋯O intra-molecular inter-actions formed by the sulfone oxygen atoms, which generate two S(5) ring motifs. In the crystal of I, N-H⋯O hydrogen bonds link the mol-ecules into R ² ₂(8) ring

SUBMITTER: Madhan S 

PROVIDER: S-EPMC10439409 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature