BinaRena: a dedicated interactive platform for human-guided exploration and binning of metagenomes.

ABSTRACT:

Background

Exploring metagenomic contigs and "binning" them into metagenome-assembled genomes (MAGs) are essential for the delineation of functional and evolutionary guilds within microbial communities. Despite the advances in automated binning algorithms, their capabilities in recovering MAGs with accuracy and biological relevance are so far limited. Researchers often find that human involvement is necessary to achieve representative binning results. This manual process however is expertise demanding and labor intensive, and it deserves to be supported by software infrastructure.

Results

We present BinaRena, a comprehensive and versatile graphic interface dedicated to aiding human operators to explore metagenome assemblies via customizable visualization and to associate con

SUBMITTER: Pavia MJ 

PROVIDER: S-EPMC10439608 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature