Postoperative Acute Kidney Injury by Age and Sex: A Retrospective Cohort Association Study.

ABSTRACT:

Background

Acute kidney injury (AKI) after noncardiac surgery is common and has substantial health impact. Preclinical and clinical studies examining the influence of sex on AKI have yielded conflicting results, although they typically do not account for age-related changes. The objective of the study was to determine the association of age and sex groups on postoperative AKI. The authors hypothesized that younger females would display lower risk of postoperative AKI than males of similar age, and the protection would be lost in older females.

Methods

This was a multicenter retrospective cohort study across 46 institutions between 2013 and 2019. Participants included adult inpatients without pre-existing end-stage kidney disease undergoing index major noncardiac, nonkidney/u

SUBMITTER: Privratsky JR 

PROVIDER: S-EPMC10439699 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature