Comparative genomics unveils extensive genomic variation between populations of Listeria species in natural and food-associated environments.

ABSTRACT: Comprehending bacterial genomic variation linked to distinct environments can yield novel insights into mechanisms underlying differential adaptation and transmission of microbes across environments. Gaining such insights is particularly crucial for pathogens as it benefits public health surveillance. However, the understanding of bacterial genomic variation is limited by a scarcity of investigations in genomic variation coupled with different ecological contexts. To address this limitation, we focused on Listeria, an important bacterial genus for food safety that includes the human pathogen L. monocytogenes, and analyzed a large-scale genomic dataset collected by us from natural and food-associated environments across the United States. Through comparative genomics analyses on 449 isolate

SUBMITTER: Liao J 

PROVIDER: S-EPMC10439904 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature