Follicular steroidogenesis in random start protocols for oocyte cryopreservation.

ABSTRACT:

Purpose

Random start protocols are commonly used for oocyte cryopreservation in women with cancer. However, albeit generally reassuring, available evidence is still insufficient to rule out a sub-optimal cycle outcome. This study aimed to compare follicular steroidogenesis between women initiating the random start protocol in the luteal phase and those initiating in the follicular phase.

Methods

Consecutive women with cancer scheduled for oocyte cryostorage were prospectively recruited. We excluded those requiring a concomitant letrozole assumption. All women received a standardized protocol with recombinant FSH and GnRH antagonists. At the time of oocyte retrieval, follicular fluids were pooled, and a sample was collected and frozen at -80 °C. All samples were assayed conco

SUBMITTER: Galati G 

PROVIDER: S-EPMC10440306 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature