Racial disparity in the genomics of precision oncology of prostate cancer.

ABSTRACT:

Background

Significant racial disparities in prostate cancer incidence and mortality have been reported between African American Men (AAM), who are at increased risk for prostate cancer, and European American Men (EAM). In most of the studies carried out on prostate cancer, this population is underrepresented. With the advancement of genome-wide association studies, several genetic predictor models of prostate cancer risk have been elaborated, as well as numerous studies that identify both germline and somatic mutations with clinical utility.

Recent findings

Despite significant advances, the AAM population continues to be underrepresented in genomic studies, which can limit generalizability and potentially widen disparities. Here we outline racial disparities in currently av

SUBMITTER: Le T 

PROVIDER: S-EPMC10440844 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature